The P6 Wrist Point: What It Is and Why It's So Well Known
Quick answer ,P6, also known as Neiguan, sits on the inner forearm about three finger-widths below the wrist crease, between two central tendons. It's the point pressed by anti-nausea wristbands and is the most-studied acupressure point overall, with mixed but genuinely more substantial research behind it than most other points.

If you've read our nausea point guide, you've already met this point without the name attached. It's worth its own page because P6 is, by a wide margin, the most-researched single point in all of acupressure, and understanding why tells you something about how to read every other point on this site.
Where P6 actually is
On the inside of the forearm, palm up, about three finger-widths below the wrist crease, in the gap between the two central tendons you can feel stand up when you make a loose fist. Traditionally named Neiguan, meaning roughly "inner gate," and numbered as the sixth point on the Pericardium meridian, hence "P6."
Why this one point gets studied so much
P6 became a serious research subject because it had a ready-made, testable delivery method already in wide consumer use, the fixed-bead wristband, sold for decades for motion sickness. That made it unusually easy to design trials around: a real product, a specific point, a measurable outcome (nausea). Most other acupressure points have never had anything close to that volume of study, simply because the research infrastructure wasn't already sitting there.
What the research on P6 actually shows
Multiple trials, particularly for postoperative and pregnancy-related nausea and motion sickness, report a modest reduction in symptoms with P6 stimulation, whether from pressure, wristbands, or mild electrical stimulation. Systematic reviews are more cautious, some find the effect holds up reasonably well, others attribute more of it to placebo than enthusiasts claim. The honest summary: P6 has the strongest evidence base of any acupressure point, and that evidence is still genuinely mixed, not settled.
How to work it
Locate the spot, three finger-widths below the wrist crease, between the tendons. Use a fine point head at a low setting, this is thin tissue over tendon, and hold for one to two minutes per wrist. Full walkthrough, plus the pregnancy exclusion that applies to this point specifically, is in our nausea guide.
The honest takeaway
P6 is the point where "acupressure has some real research behind it" is most defensible, and also the clearest example of why "some research" isn't the same as "proven." Severe or persistent nausea is a medical question, not a wrist-point one.
Frequently asked questions
- Where exactly is the P6 acupressure point?
- On the inner forearm, palm facing up, roughly three finger-widths below the wrist crease, in the gap between the two central tendons. It's the same point pressed by over-the-counter motion sickness wristbands.
- Is P6 the most scientifically studied acupressure point?
- Yes, by a wide margin, largely because of the long-standing commercial wristbands built around it, which made it easy to design trials around. The evidence is more substantial than for most other points but still mixed, some trials show a modest benefit for nausea, others don't find a clear effect beyond placebo.
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